A former colleague of mine who has done some work for Harvard University in the past told me about an aging intervention called RESTORIN, which, if I recall correctly, he learned about while working there. He described his subjective experience with the product of elevated energy with such positive exuberance that it was almost as though I could tell a few years had been turned back on his age, especially his cognitive age, just within the three months that he had started taking it. Whether my perception of my friend turning back the clock on his overall health had anything to do with the product’s actual effects got the wheels in my head spinning. With that, I did some research on the aging intervention technologies within RESTORIN and then took a leap and decided to try RESTORIN for myself.

My Research Providing a Rationale to Buy RESTORIN

The package arrived at my doorstep — one small box that contained two bottles, each including 60 capsules, which may or may not hold the answer to extending my years without any diseases. Even though my purchase of RESTORIN came with a steep price tag, perusing the product’s background, as provided by my friend who has worked with Harvard, piqued my interest. This was especially the case since it integrates the most well-established aging intervention technologies from high-profile institutions that are strengthened by Seragon Biosciences’ expertise in pharmaceutical research and development. The institutions that Seragon collaborated with, such as Harvard University, Mayo Clinic, and Scripps Research, produced what some in science recognize as one of the most effective aging interventions.

With this in mind, I wondered whether researchers at Seragon and these top-tier institutions had made any progress in developing high-grade technologies that might quell the ravages of age-related physiological decline. Thus, before I made the purchase, I did further research of my own, first on the burgeoning aging research field and then on the compounds contained in RESTORIN.

A bottle of RESTORIN capsules
(A bottle of RESTORIN capsules)

Well-Informed Consumers Familiar with the Data May Acquire RESTORIN as an Aging Intervention

Human longevity studies are extremely difficult and expensive to carry out. In that regard, following people for their lifespans while tracking different health parameters would take decades, and most people do not have the time to sit around and wait for results.

For these reasons, Seragon has decided to make its RESTORIN nutraceutical capsules available to consumers who have sufficient knowledge to understand what the animal data means and can afford the high price.

Technologies in RESTORIN

As for the scientific data associated with the product, RESTORIN contains a combination of compounds that may act together to amplify the effects that any of them may have on their own. Although not explicitly stated on RESTORIN’s website, this may be based on research showing that certain compound combinations enhance effects against aging.

I first perused over a press release pertaining to Seragon’s drug candidate SRN-901, which serves as a basis for RESTORIN. What first caught my attention was that, according to the press release, SRN-901 contains an inhibiting component for the protein complex mTOR. I had done my research on the promising compound rapamycin that some people are taking to ward off aging and knew that rapamycin’s key mechanism of action is believed to also be through mTOR inhibition. Interestingly, mTOR works by controlling cellular metabolism, survival, and proliferation, and researchers believe that by inhibiting it, we can mimic the effects of calorie restriction, the most effective means we know of to extend mouse and monkey lifespan.

Human trials are still necessary to fully grasp whether calorie restriction or compounds that mimic the effects of calorie restriction extend human lifespan. At the same time, the promising findings from mouse and monkey studies suggest that calorie restriction may have an effect on extending the years we live without disease—our healthspan.

I also found that RESTORIN contains autophagy and mitophagy activators. Autophagy is a cellular process whereby waste and dysfunctional proteins get disposed of, and mitophagy is the degradation of malfunctioning cell powerhouses—mitochondria. These mechanisms are crucial for the maintenance of cell function. Thus, the possibility lingers that activating autophagy and mitophagy helps restore proper cellular operation as we get older.

I moved on to checking into compounds known as senolytics contained in RESTORIN. Senolytics have received more and more attention recently, because they may serve as a way to eliminate dysfunctional cells that accumulate as we get older called senescent cells. Senescent cell accumulation constitutes a critical hallmark of aging, and research in rodents suggests that eliminating them with senolytics not only extends lifespan but rejuvenates various organs such as the heart.

What’s more, I found that RESTORIN contains a nicotinamide adenine dinucleotide (NAD+) precursor, known to counter an age-related drop in NAD+ levels. This may be important since proteins linked to aging that control metabolic activity, cell survival, inflammation, and DNA repair called sirtuins need sufficient NAD+ for their function. Not only that, but the renowned Harvard genetics professor Dr. David Sinclair has long touted the potential benefits of NAD+ precursors after having found that using one improves physical endurance in elderly mice.

Subjective Perception of Enhanced Energy Levels

After going through all of this research and taking RESTORIN for a few months, I noticed some effects. I cannot say with certainty that these effects are not attributable to the placebo effect, but I did notice some changes, including more hair growth.

Not only that but my energy levels seemed to increase. The energy I have throughout the day after taking RESTORIN does not induce jitters or make me anxious. Rather, it seems like I have sustained levels of elevated energy, which do not taper off with a crash as with consuming excessive caffeine.

I believe the enhanced energy that I experience improves my focus since I am more able to get things done at work. Moreover, I do not have to fight with myself to start exercising; I notice that my adherence to a physical fitness regimen has improved.

With all of that said, I plan to continue taking RESTORIN for the foreseeable future. If the physical energy and enhanced cognition I perceive from taking RESTORIN are actually real, I want to continue to experience these effects. I am also curious to find whether my biological age—a measure of your age based on how well your tissues and organs function—has diminished over the few months that I have been taking RESTORIN. Like the others who have decided to take RESTORIN, I am participating in a quest to slow the aging process in my body. Only time will tell whether this is a fruitful endeavor. Moreover, whether RESTORIN makes me live longer is one question, but so far, the improvements in how I feel seem to make my purchase worthwhile.