People in Blue Zones—regions where higher percentages of people live past 100—eat ample amounts of plant-derived compounds called polyphenols, which modulate hallmarks of aging.

A formulation of 10 human-derived probiotics — beneficial gut bacteria — counter Alzheimer’s progression and improve gut health in mice.

A mix of filtered milk, egg yolk extract, nicotinamide mononucleotide (NMN), quercetin, ɑ-ketoglutarate, white button mushroom, and celery seed extract enhances immune cell killing action against cancer cells.

Cellular reprogramming, a technique currently being investigated as an age-reversal therapy, helps a paralyzed man walk again by regenerating his spinal cord neurons.

María Branyas Morera died last year at the phenomenal age of 117, and a new study of her medical features reveals some possible longevity-promoting characteristics like beneficial gut bacteria.

Both NMN (nicotinamide mononucleotide) and NR (nicotinamide riboside) are converted to NA (nicotinic acid) by the gut before being made into NAD+ (nicotinamide adenine dinucleotide).

Scripps researchers show that diAcCA, a rosemary-derived compound, can mitigate two hallmarks of Alzheimer’s and improve spatial memory and learning.

The most measured man in the world, Bryan Johnson, reveals his results from 90 days of hyperbaric oxygen therapy.

Scientists find that a GLP-1 receptor agonist similar to the weight loss drug Ozempic activates sirtuins to modulate bone health in rats.

According to Retro Biosciences CEO Joe Betts-LaCroix, a whopping 85% of healthcare pertains to treating aging-related ailments, and he unveils three of his company’s strategies to mitigate them.

Researchers unveil data suggesting that extreme outdoor heat in US regions like Phoenix, Arizona accelerates the pace of aging in older adults.

In older adults, liposomal NMN — NMN carried in membranes — increases NAD+ (nicotinamide adenine dinucleotide) levels more than non-liposomal NMN.

Rising interest in longevity has spawned disease-prevention clinics like Peter Attia’s Biograph, Matt Kaeberlein’s Optispan, and J. Craig Venter’s Human Longevity.

Research highlighted by Harvard’s David Sinclair shows that nail growth declines by 0.5% per year after age 25, suggesting it may serve as a measurable indicator of biological aging.

A new sirtuin 3 activator with stronger effects than NAD+ precursor NMN will enter clinical trials in 2025, targeting Alzheimer’s and other age-related diseases.