SPOTLIGHTScientists Unveil Results from Human Trial Directly Comparing Three NAD+ Precursors
A direct comparison of NAD+ precursors in humans shows that NMN and NR double circulating NAD+ after two weeks of supplementation, while Nam does not.
Seragon’s Breakthrough Longevity Candidate SRN-901 Dramatically Increases Lifespan and Healthspan in Preclinical Study
Seragon Biosciences has completed one of the most comprehensive preclinical studies to date, finding that its aging intervention candidate SRN-901 drastically prolongs lifespan and healthspan.
Anti-Aging Drug Metformin Counteracts Age-Related Vision Deficits, New Study Shows
Metformin—a repurposed FDA-approved drug—prevents impairments in visual processing in aged mice.
New Study Finds Astronauts May Be Ideal Aging Models for Therapeutic Testing
Spaceflight exposes astronauts to age-inducing environmental stressors, and a new study finds that, on average, it accelerates biological age—an assessment reflecting how well cells are aging.
Urolithin A vs Spermidine for Longevity: Benefits, Pathways, and Differences
While urolithin A and spermidine both target cellular maintenance, urolithin A targets the function of the cell’s powerhouses (mitochondria) more, and spermidine has broader pro-longevity effects.
The Secret to Delaying Aging and Treating Chronic Stress: New Theory
Preserving mitochondrial health may be the key to preventing cellular aging, and scientists reveal tactics for doing so, according to their new theory.
Scientists Predict that Lifestyle Can Extend Lifespan by at Most One Year
Rather than lifestyle, substantially extending lifespan may involve reducing cellular damage and increasing damage removal, potentially with known longevity interventions.
Life-Extending Molecule Alpha-Ketoglutarate Protects Against Brain Aging, New Study Shows
Alpha-ketoglutarate improves memory-formation capacity in mice that model brain aging.
Scientists Uncover Evidence That Molecule Released During Exercise, Also Available as a Supplement, Slows Cognitive Decline with Age
According to a new study, whether from exercise or supplementation, increased levels of β-hydroxybutyrate (a molecule primarily released from the liver during fasting or aerobic exercise) improve cognition in old mice.
Calorie Restriction Preserves Brain White Matter by Slowing Cellular Aging: New Study Shows
A new primate study shows long-term calorie restriction preserves brain white matter by slowing age-related changes in oligodendrocytes and microglia.
- Aging & Longevity
Seragon’s Breakthrough Longevity Candidate SRN-901 Dramatically Increases Lifespan and Healthspan in Preclinical Study
Seragon Biosciences has completed one of the most comprehensive preclinical studies to date, finding that its aging intervention candidate SRN-901 drastically prolongs lifespan and healthspan.
- Neurological
Anti-Aging Drug Metformin Counteracts Age-Related Vision Deficits, New Study Shows
Metformin—a repurposed FDA-approved drug—prevents impairments in visual processing in aged mice.
- Aging & Longevity
New Study Finds Astronauts May Be Ideal Aging Models for Therapeutic Testing
Spaceflight exposes astronauts to age-inducing environmental stressors, and a new study finds that, on average, it accelerates biological age—an assessment reflecting how well cells are aging.
- Aging & Longevity
Urolithin A vs Spermidine for Longevity: Benefits, Pathways, and Differences
While urolithin A and spermidine both target cellular maintenance, urolithin A targets the function of the cell’s powerhouses (mitochondria) more, and spermidine has broader pro-longevity effects.
- Metabolism
The Secret to Delaying Aging and Treating Chronic Stress: New Theory
Preserving mitochondrial health may be the key to preventing cellular aging, and scientists reveal tactics for doing so, according to their new theory.
- Aging & Longevity
Scientists Predict that Lifestyle Can Extend Lifespan by at Most One Year
Rather than lifestyle, substantially extending lifespan may involve reducing cellular damage and increasing damage removal, potentially with known longevity interventions.
- Neurological
Life-Extending Molecule Alpha-Ketoglutarate Protects Against Brain Aging, New Study Shows
Alpha-ketoglutarate improves memory-formation capacity in mice that model brain aging.
- Neurological
Scientists Uncover Evidence That Molecule Released During Exercise, Also Available as a Supplement, Slows Cognitive Decline with Age
According to a new study, whether from exercise or supplementation, increased levels of β-hydroxybutyrate (a molecule primarily released from the liver during fasting or aerobic exercise) improve cognition in old mice.
- Neurological
Calorie Restriction Preserves Brain White Matter by Slowing Cellular Aging: New Study Shows
A new primate study shows long-term calorie restriction preserves brain white matter by slowing age-related changes in oligodendrocytes and microglia.
STUDIES
NEWS
The Vitalists Explained: A Longevity Movement Aiming to Shape Politics
The Vitalists argue that society needs a revolution for the sake of lifespan extension, and a growing number of scientists, investors, and politicians are taking them seriously.
Supplementing with Naturally Produced Metabolic Molecules to Promote Longevity
Naturally produced molecules mediate metabolic cues that link calorie restriction to pro-longevity effects, and supplementing with them may aid in extending healthy lifespan.
Longevity Supplement Combo Boosts Muscle Mass and Endurance, New Study Shows
Fructooligosaccharides (FOS) and ellagic acid (EA) enhance muscular endurance and mass by targeting gut bacteria urolithin A biosynthesis in mice.
Scientists Unveil Results from Human Trial Directly Comparing Three NAD+ Precursors
A direct comparison of NAD+ precursors in humans shows that NMN and NR double circulating NAD+ after two weeks of supplementation, while Nam does not.
Anti-Aging Drug Metformin Counteracts Age-Related Vision Deficits, New Study Shows
Metformin—a repurposed FDA-approved drug—prevents impairments in visual processing in aged mice.
New Study Finds Astronauts May Be Ideal Aging Models for Therapeutic Testing
Spaceflight exposes astronauts to age-inducing environmental stressors, and a new study finds that, on average, it accelerates biological age—an assessment reflecting how well cells are aging.
Urolithin A vs Spermidine for Longevity: Benefits, Pathways, and Differences
While urolithin A and spermidine both target cellular maintenance, urolithin A targets the function of the cell’s powerhouses (mitochondria) more, and spermidine has broader pro-longevity effects.
The Secret to Delaying Aging and Treating Chronic Stress: New Theory
Preserving mitochondrial health may be the key to preventing cellular aging, and scientists reveal tactics for doing so, according to their new theory.
Scientists Predict that Lifestyle Can Extend Lifespan by at Most One Year
Rather than lifestyle, substantially extending lifespan may involve reducing cellular damage and increasing damage removal, potentially with known longevity interventions.
Life-Extending Molecule Alpha-Ketoglutarate Protects Against Brain Aging, New Study Shows
Alpha-ketoglutarate improves memory-formation capacity in mice that model brain aging.
Calorie Restriction Preserves Brain White Matter by Slowing Cellular Aging: New Study Shows
A new primate study shows long-term calorie restriction preserves brain white matter by slowing age-related changes in oligodendrocytes and microglia.
Scientists Uncover Evidence That Molecule Released During Exercise, Also Available as a Supplement, Slows Cognitive Decline with Age
According to a new study, whether from exercise or supplementation, increased levels of β-hydroxybutyrate (a molecule primarily released from the liver during fasting or aerobic exercise) improve cognition in old mice.
Stem Cell–Derived Vesicles Rejuvenate Pancreas Cells and Cure Age-Related Diabetes
Stem cell–derived vesicles rejuvenate aging pancreatic β cells, restore insulin secretion, and reverse diabetes in old mice by reducing cellular senescence and improving mitochondrial function.
New Aging Theory Helps Build the Case for Devices That Activate Key Nerve
A new aging theory posits that an increasing age-related imbalance between collections of nerves triggering “fight or flight” and “rest and repair” responses underlies core aging processes.
Engineering the Future: The AI Revolution in Aging Science
A new perspective article explores how artificial intelligence (AI)-based coordinated research may revolutionize the fight against aging.